Currently, you are not logged in to my.chemeurope.com. Therefore, you can remember a maximum of 5 contents.
CareX and Chemical Diversity Labs announce research agreement
French biopharmaceutical company CareX S.A. and San Diego based Chemical Diversity Labs, Inc. announced that they have formed a research collaboration that applies methods of rational drug design to Focused Library Screening of bio-active substances.
Under the terms of the agreement, Chemical Diversity Labs, Inc. will provide several lead-enriched libraries for CareX's drug discovery targets in the field of metabolic diseases. ICM protein modeling and flexible docking software platform designed by Chemical Diversity's partner MolSoft (San Diego, CA, USA) was used to find potential binders of CareX's targets. Chemical Diversity Labs, Inc. then produced arrays of potential ligands in parallel synthesis and additionally selected likely binding molecules from its world's largest commercial diverse collection of 400,000 small molecules.
Dr. Jurgen Lehmann, CSO of CareX, and Dr. Stanley Lang, VP Chemistry of Chemical Diversity Labs, Inc., were equally excited about the opportunity of joining the possibilities of rational drug design and modern small molecule synthesis with the target knowledge and screening technology of CareX. The new approach of screening a set of maximum diverse compounds as well as several focused libraries on similar targets for an optimized search of the available chemical space for hits was jointly developed by CareX and Chemical Diversity Labs, Inc.
- research collaborations
- parallel synthesis
- metabolic diseases
- ligands
- ICM
- drug design
- chemistry
- bioactives
- 1Turning abandoned mines into batteries
- 2Solar-powered system converts plastic and greenhouse gases into sustainable fuels
- 3Scientists unveil least costly carbon capture system to date
- 4Discovery of new ice may change understanding of water
- 5New ‘chain mail’ material of interlocking molecules is tough, flexible and easy to make
- 6Turning plastic waste into a valuable soil additive
- 7Entire colour palette of inexpensive fluorescent dyes
- 8From the road to the plate: lettuce takes up toxic additives from tyre wear
- 9Farewell to ‘forever’ – Destroying PFAS by grinding it up with a new additive
- 10Superconductivity at room temperature soon?
- Energy crisis could become a win-win situation for climate and the economy
- Covestro successfully starts up a new world-scale chlorine plant in Tarragona
- Science-based industries join forces to address UK net zero targets
- Covestro plans to close the Markt Bibart site
- Adam Chong named new CEO of Rigaku Asia Pacific