ChemNavigator's iResearch Library Tops 5 Million Samples For Use in Drug Discovery

iResearch(TM) Library Now Accessible Through New 3-DPL(TM) Map Virtual Screening Collaborations

19-Feb-2003

ChemNavigator, a discovery-informatics company, announced today that its iResearch(TM) Library has grown to include over five million chemical samples from over 80 commercial and academic supplier sources around the world. The iResearch(TM) Library is a constantly updated compendium of commercially accessible chemistry for drug discovery. Research companies and institutions use the iResearch Library information for compound selection, SAR searches, and virtual screening programs. Pharmaceutical and biotechnology research companies may license the iResearch Library data on CD-ROM or may access the same data through ChemNavigator's on-line iResearch System application. "It's a challenge for research organizations to keep up with the constantly changing world wide inventory of commercially available chemistry," comments Dr. Tad Hurst, chief technical officer for ChemNavigator. "Our staff processes over one million chemical sample records each month by adding new chemistry and removing out-dated chemical sample records. All chemical structure records are checked and adjusted for compliance with standard chemistry rules." ChemNavigator is expanding the commercial access to the iResearch Library to include virtual screening services. With ChemNavigator's new 3-Dimensional Protein-Ligand Mapping technology (3-DPL(TM) Map) ChemNavigator scientists can select chemical libraries designed to show high biological affinity for a discovery partner's drug target. In addition, as new chemical samples are registered into the iResearch Library, 3-DPL Map evaluates each sample structure for potential binding affinity to the research partner's drug target. Over the past 1.5 years, Dr. Hurst's research group at ChemNavigator has developed and filed patents around 3-DPL Map technology. 3-DPL Map has been scientifically validated through comparison of 3-DPL Map results with experimentally determined co-crystallized ligand binding studies.

https://www.chemeurope.com/en/news/20506/chemnavigator-s-iresearch-library-tops-5-million-samples-for-use-in-drug-discovery.html