The only "chemoselective" sense of human kind is the sense of smell. Through this sense we are able to perceive taste, aroma, and hazardous substances, such as hydrogen sulfide. Unfortunately, this sense is evolutionarily hampered for human beings compared to animals like dogs, for instance. Also from a technological perspective there is no sensitive and selective "electronic nose" available, yet. Therefore, we strive to provide a novel sensor technology based on ambient mass spectrometry which does not only improve the utilization in traditional laboratory environments, but also enables the transfer of this kind of sensor technology to industrial process control, forensics, security technology (drugs, explosives, etc.) and the medical "point of care" diagnostics.