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Systematic (IUPAC) name
phenyl]propanoic acid
CAS number 31842-01-0
ATC code M01AE10
PubChem 3718
Chemical data
Formula C17H15NO3 
Mol. mass 281.306 g/mol
Pharmacokinetic data
Bioavailability High (rapid and complete absorption)
Metabolism Glucuronidation
Half life 2.3 hours
Excretion Renal
Therapeutic considerations
Pregnancy cat.


Legal status


Routes Oral

Indoprofen is a non-steroidal anti-inflammatory drug. It was withdrawn worldwide in the 1980s after postmarketing reports of severe gastrointestinal bleeding.[1]

A 2004 study using high-throughput screening found indoprofen to increase production of the survival of motor neuron protein, suggesting it may provide insight into treatments for spinal muscular atrophies.[1][2]


  1. ^ a b Frazin, Natalie (March 9 2005). Pain Reliever May Provide Clues for Treating Spinal Muscular Atrophy. United States National Institute of Neurological Disorders and Stroke. Retrieved on 2007-10-06.
  2. ^ Lunn MR, Root DE, Martino AM, et al (2004). "Indoprofen upregulates the survival motor neuron protein through a cyclooxygenase-independent mechanism". Chem Biol 11 (11): 1489–93. doi:10.1016/j.chembiol.2004.08.024. PMID 15555999.

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Indoprofen". A list of authors is available in Wikipedia.
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