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Nabumetone



Nabumetone
Systematic (IUPAC) name
4-(6-methoxy-2-naphthyl)-2-butanone
Identifiers
CAS number 42924-53-8
ATC code M01AX01
PubChem 4409
DrugBank APRD01128
Chemical data
Formula C15H16O2 
Mol. mass 228.29 g/mol
Pharmacokinetic data
Bioavailability  ?
Protein binding > 99% (active metabolite)
Metabolism Hepatic, to active metabolite 6-methoxy-2-naphthylacetic acid
Half life 23 hours (active metabolite)
Excretion Renal
Therapeutic considerations
Pregnancy cat.

?

Legal status
Routes Oral

Nabumetone is a non-steroidal anti-inflammatory drug of the arylalkanoic acid family (which includes diclofenac). Marketed under the brand name Relafen, it has been shown to have a slightly lower risk of gastrointestinal side effects than most other non-selective NSAID's.

Additional recommended knowledge


 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Nabumetone". A list of authors is available in Wikipedia.
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