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Systematic (IUPAC) name
2-(3-fluoro-4-phenyl-phenyl)propanoic acid
CAS number 5104-49-4
ATC code M01AE09 M02AA19, S01BC04
PubChem 3394
DrugBank APRD00753
Chemical data
Formula C15H13FO2 
Mol. mass 244.261 g/mol
Pharmacokinetic data
Bioavailability  ?
Protein binding > 99%
Metabolism Hepatic (CYP2C9)
Half life 4.7-5.7 hours
Excretion Renal
Therapeutic considerations
Pregnancy cat.

C (U.S.), B2 (Au)

Legal status
Routes Oral

Flurbiprofen is a member of the phenylalkanoic acid derivative family of non-steroidal anti-inflammatory drugs (NSAIDs) used to treat the inflammation and pain of arthritis. It is also known by the trade name ANSAID and marketed by Pfizer.

Flurbiprofen is also used as an active ingredient in some kinds of throat lozenges.

R-flurbiprofen is the single enantiomer of racemate flurbiprofen; this compound is currently in clinical trials for the treatment of metastatic prostate cancer, and Alzheimer's disease.

Flurbiprofen was mocked by television satirist Stephen Colbert (for its unlikely name) during an interview with Terry Gross aired on October 9, 2007 on National Public Radio's program "Fresh Air." Colbert had been taking the drug after breaking his wrist earlier that year.

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Flurbiprofen". A list of authors is available in Wikipedia.
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