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Iproniazid



Iproniazid
Systematic (IUPAC) name
N'-propan-2-ylpyridine-4-carbohydrazide
Identifiers
CAS number 54-92-2
ATC code N06AF05
PubChem 3748
Chemical data
Formula C9H13N3O 
Mol. mass 179.219
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
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Excretion  ?
Therapeutic considerations
Pregnancy cat.

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Legal status

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Iproniazid (iproniazid phosphate, marketed under the names Marsilid®, Iprozid®, Ipronid®, Rivivol®, Propilniazida®) is a monoamine oxidase inhibitor (MAOI) that was developed as the first anti-depressant. It was originally intended to treat tuberculosis when it was discovered that patients given iproniazid became "inappropriately happy," subsequently with further research iproniazid was marketed specifically for depression in 1958. It was later replaced by less hepatotoxic drugs, particularly isocarboxazid.

 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Iproniazid". A list of authors is available in Wikipedia.
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