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Pargyline



Pargyline
Systematic (IUPAC) name
N-Benzyl-N-methyl-prop-2-yn-1-amine
Identifiers
CAS number 555-57-7
ATC code C02KC01 C02LL01
PubChem 4688
Chemical data
Formula C11H13N 
Mol. mass 195.69 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

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Legal status
Routes  ?

Pargyline is a monoamine oxidase B (MAO-B) inhibitor. It functions by inhibiting the metabolism of catecholamines and tyramine within presynaptic nerve terminals. Patients taking pargyline must avoid concurrent consumption of tyramine-containing foods such as bleu cheese and beer, as this can lead to a hypertensive crisis.[1]

Additional recommended knowledge


References

  1. ^ Tulane University School of Medicine Department of Pharmacology: Autonomic Drug Profile handout, October 2006
 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Pargyline". A list of authors is available in Wikipedia.
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