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Medroxyprogesterone



Medroxyprogesterone
Systematic (IUPAC) name
17-acetyl-17-hydroxy- 6,10,13-trimethyl- 1,2,6,7,8,9,10,11,12,13,14,15,16, 17- tetradecahydrocyclopenta[a] phenanthren-3-one
Identifiers
CAS number 520-85-4
ATC code G03AC06 G03DA02, L02AB02
PubChem 10631
DrugBank APRD00627
Chemical data
Formula C22H32O3 
Mol. mass 344.488 g/mol
Pharmacokinetic data
Bioavailability  ?
Protein binding 90%
Metabolism  ?
Half life 50 days
Excretion  ?
Therapeutic considerations
Pregnancy cat.

?

Legal status
Routes  ?

Medroxyprogesterone is a progestin, and is commonly a component of hormonal contraceptives. It can be used in the treatment of endometriosis, abnormal menstrual bleeding or amenorrhea.[1][2] Possible side effects include weight gain, depression, and irregular menses or amenorrhea.

References

  1. ^ http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a682470.html
  2. ^ http://www.medicinenet.com/medroxyprogesterone/article.htm

See also


v • d • e
Sex hormones and related agents (primarily G03, also L02, H01C) - human endogenous in CAPS
Progestogens:
(receptor)		PROGESTERONE, Desogestrel, Drospirenone, Dydrogesterone, Ethisterone, Etonogestrel, Ethynodiol diacetate, Gestodene, Gestonorone, Levonorgestrel, Lynestrenol, Medroxyprogesterone, Megestrol, Norelgestromin, Norethisterone, Norethynodrel, Norgestimate, Norgestrel, Norgestrienone, Tibolone
Selective progesterone receptor modulator: Asoprisnil, CDB-4124
Antiprogestogen: Mifepristone
Androgens:
(receptor)		TESTOSTERONE, Androstanolone, Fluoxymesterone, Mesterolone, Methyltestosterone, (see also anabolic steroids)
Antiandrogens: Bicalutamide, Cyproterone, Flutamide, Nilutamide, Spironolactone
Estrogens:
(receptor)		ESTRADIOL, ESTRIOL, ESTRONE, Chlorotrianisene, Dienestrol, Diethylstilbestrol, Ethinylestradiol, Fosfestrol, Mestranol, Polyestradiol phosphate
Selective estrogen receptor modulator: Bazedoxifene, Clomifene, Fulvestrant, Lasofoxifene, Raloxifene, Tamoxifen, Toremifene
Aromatase inhibitor: Aminogluthetimide, Anastrozole, Exemestane, Formestane, Letrozole, Vorozole
Gonadotropins:
(FSHR/LHCGR)		ovulation stim.: Clomifene, Urofollitropin
Antigonadotropins: Danazol, Gestrinone
GnRH:
(receptor)		agonist: Buserelin, Goserelin, Histrelin, Leuprorelin, Nafarelin, Triptorelin
antagonist: Abarelix, Cetrorelix, Ganirelix
 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Medroxyprogesterone". A list of authors is available in Wikipedia.
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