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Thiothixene



Thiothixene
Systematic (IUPAC) name
(Z)-N,N-dimethyl-9-
[3-(4-methylpiperazin-1-yl)propylidene]-
thioxanthene-2-sulfonamide
Identifiers
CAS number 5591-45-7
ATC code N05AF04
PubChem 5454
DrugBank none
Chemical data
Formula C23H29N3O2S2 
Mol. mass 443.627
Pharmacokinetic data
Bioavailability  ?
Metabolism Hepatic
Half life 10-20 hours
Excretion  ?
Therapeutic considerations
Pregnancy cat.

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Legal status

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Routes oral

Thiothixene (sold as Navane) is a thioxanthene drug used as a typical antipsychotic medication. It is a thioxanthene derivative and is the cis isomer of N,Ndimethyl- 9-[3-(4-methyl-1-piperazinyl)-propylidene] thioxanthene-2-sulfonamide.

Additional recommended knowledge

Although widely used in the treatment of schizophrenia for several decades, thiothixene is seldom used today in favor of atypical antipsychotics such as risperidone.


 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Thiothixene". A list of authors is available in Wikipedia.
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