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Molindone



Molindone
Systematic (IUPAC) name
3-ethyl-2-methyl-5-(morpholin-4-ylmethyl)-
1,5,6,7-tetrahydro-4H-indol-4-one
Identifiers
CAS number 7416-34-4
ATC code N05AE02
PubChem 23897
Chemical data
Formula C16H24N2O2 
Mol. mass 276.374 g/mol
SMILES search in eMolecules, PubChem
Pharmacokinetic data
Bioavailability  ?
Metabolism Hepatic
Half life 1.5 hours
Excretion Minor, renal and fecal
Therapeutic considerations
Pregnancy cat.

C(US)

Legal status

-only(US)

Routes Oral

Molindone is a therapeutic antipsychotic, used in the treatment of schizophrenia.[1] It works by blocking the effects of dopamine in the brain, leading to diminished psychoses. It is rapidly absorbed when taken by mouth.

Additional recommended knowledge

Molindone is sold under the product name Moban.

Adverse effects

Main article: Typical antipsychotic

The side effect profile of molindone is similar to that of other typical antipsychotics. Unlike most antipsychotics, however, molindone use is associated with weight loss.[2][3]

See also

References

  1. ^ molindone (web). F.A. Davis Company. Retrieved on 2007-11-04.
  2. ^ Bagnall A, Fenton M, Kleijnen J, Lewis R (2007). "Molindone for schizophrenia and severe mental illness". Cochrane Database Syst Rev (1): CD002083. doi:10.1002/14651858.CD002083.pub2. PMID 17253473.
  3. ^ Allison DB, Mentore JL, Heo M, et al (1999). "Antipsychotic-induced weight gain: a comprehensive research synthesis". Am J Psychiatry 156 (11): 1686–96. PMID 10553730. Free full text
 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Molindone". A list of authors is available in Wikipedia.
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