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Systematic (IUPAC) name
CAS number 749-13-3
ATC code N05AD02
PubChem 5567
Chemical data
Formula C22H23F4NO2 
Mol. mass 409.417 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.


Legal status
Routes Oral

Trifluperidol is a drug which is a butyrophenone derivative. It has general properties similar to those of haloperidol, but is considerably more potent by weight, and causes relatively more severe side effects, especially tardive dyskinesia and other extrapyramidal effects. It is used in the treatment of psychoses including mania and schizophrenia.

Trifluperidol was discovered at Janssen Pharmaceutica in 1959.


  • Gallant DM, Bishop MP, Timmons E, Steele CA, A controlled evaluation of Trifluperidol: a new potent psychopharmacologic agent, Curr Ther Res Clin Exp. 1963 Sep;27:463-71.
  • Gallant DM, Bishop MP, Timmons E, Steele CA, Trifluperidol: a butyrophenone derivative, Am J Psychiatry. 1963 Nov;120:485-7.

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Trifluperidol". A list of authors is available in Wikipedia.
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