16-Apr-2013 - University of Notre Dame

Squaraine rotaxane shuttle as a ratiometric deep-red optical chloride sensor

Chloride ions are central to many biological processes and measuring the concentration of chloride ions in biological fluids can help diagnose a number of diseases, including cystic fibrosis. Scientists from the US have synthesised a squaraine rotaxane which can detect chloride ions via colorimetric naked eye detection and fluorescence. This is the first example of a ratiometric chloride sensor that emits in the deep red region.

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