 |
|
|
|
|
|
|
Article 1 - 5 of 50 |
|
Characterization of micelles and liposomes using the Eclipse 3+ AF4 separation system coupled to a DAWN HELEOS II MALS detector
Micelles and liposomes can serve as vehicles used to solubilize and carry bioactive compounds to their site of action, thus increasing their bioavailability. First experience has been made using vitamins and enzymes as functional food additives. Moreover, micelles could be useful to deliver drugs to a defined site of action, thus reducing frequently occurring side effects of systemic drug administration. Micelles are true nano-materials with a size range of 10 to 30 nm in diameter. Ideally, they should have a narrow size distribution. Furthermore, they have to be stable and should release their active compound only in the target region. Characterization of the micelle suspensions is vital to guarantee these properties and has to cover several aspects. One important point is size distribution, which has to be determined with high resolution...
|
|
Absolute Molar Mass Characterisation
Multi-angle light scattering coupled to SEC or other fractionation methods can provide an absolute means for measuring the molar mass, size and distribution of proteins, polymers and particles of all sorts. Wyatt Technology's MALS also enables the elucidation of additional data such as branching, conformation, and eluent behaviour. The same instrumentation also allows observation of molecular interactions in a real-time environment. As MALS is an absolute mass and size measuring technique it is insensitive to the separation mechanism and as such is ideal for both highly variable research applications as well as routine quality assurance of previously characterised samples...
|
|
The Danger of Air & Bubbles
Potential Problems with Hydraulic Lubrication
Air and bubbles, or fluid aeration and cavitation, can cause numerous problems in a hydraulic and lubrication oil system. Lubrication practitioners should be attentive to abnormal noise, poor component response due to spongy behavior of aerated fluids and high fluid temperature as signs of poor lubricant health...
|
|
Calculating VOCs: Not all Low-VOCs Are Considered Equal
Like most coatings, paints, and maintenance products, water repellents are expected to comply with increasingly stringent regulations of Volatile Organic Compounds (VOC), which are any volatile carbon compounds that engage in atmospheric photochemical reactions. The simplest example of a VOC would be a solvent or drying aid. Common examples include alcohols (such as IPA), mineral spirits, kerosene, toluene or xylene. The only compounds that have been exempt from regulations are those that have shown negligible photochemical reactivity, such as volatile methyl siloxanes, acetone, and tertiary butyl acetate. Conflicts between application specifications that require higher VOC products and tightening regulation standards pose a challenge to the market...
|
|
Compressor Oils for the Chemical Industry
The chemical industry relies on very special processing to manufacture many of its products and often times include the use of compressors to achieve the special process conditions required. The selection of a lubricant is not always as easy as relying on the equipment manufacturer's recommendations. This issue of the Molykote Smart Lubrication Series highlights some of the potential scenarios that can occur and why selecting the best lubricant is so important for compressors used in the Chemical Industry. The Molykote product line has in it, specialty oils designed for many of these exact applications...
|
|
|
|
|
|
|
|
Top
