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Ketanserin is a serotonin receptor antagonist. It has the highest affinity for the serotonin 5-HT2A receptor, but also binds less potently to the 5-HT2C, 5-HT2B, 5-HT1D, alpha-adrenergic, and dopamine receptors. With tritium radioactively labeled ketanserin is used as a radioligand for the serotonin 5-HT2A receptor, e.g. in receptor binding assays.
Additional recommended knowledge
Ketanserin was discovered at Janssen Pharmaceutica in 1980.
|This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Ketanserin". A list of authors is available in Wikipedia.|