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Systematic (IUPAC) name
1-[4-(3-methylphenyl) aminopyridin-3-yl] sulfonyl-3-propan-2-yl-urea
CAS number 56211-40-6
ATC code C03CA04
PubChem 41781
DrugBank APRD00217
Chemical data
Formula C16H20N4O3S 
Mol. mass 348.421 g/mol
SMILES search in eMolecules, PubChem
Pharmacokinetic data
Bioavailability 80-90%
Protein binding Highly bound (>99%).
Metabolism Hepatic (80%)
Half life 3.5 hours; Cirrhosis: 7-8 hours
Excretion  ?
Therapeutic considerations
Pregnancy cat.


Legal status


Routes Oral, IV

Torasemide (rINN) or torsemide (USAN) is a pyridine-sulfonylurea type loop diuretic mainly used in the management of edema associated with congestive heart failure. It is also used at low doses for the management of hypertension. It is marketed under the brand name Demadex.

Compared to other loop diuretics, torasemide has a more prolonged diuretic effect than equipotent doses of furosemide and relatively decreased potassium-loss. There is no evidence of torasemide-induced ototoxicity demonstrated in humans (Dunn et al., 1995).


  • Dunn CJ, Fitton A, Brogden RN. Torasemide. An update of its pharmacological properties and therapeutic efficacy. Drugs. 1995 Jan;49(1):121-42. PMID 7705212
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Torasemide". A list of authors is available in Wikipedia.
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