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Levobetaxolol



Levobetaxolol
Systematic (IUPAC) name
(S)-1-[p-[2-(cyclopropylmethoxy)ethyl]phenoxy]-3-(isopropylamino)-2-propanol hydrochloride
Identifiers
CAS number 93221-48-8
ATC code  ?
PubChem 60657
Chemical data
Formula C18H29NO3 
Mol. mass 342.472 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life 20 hours
Excretion  ?
Therapeutic considerations
Pregnancy cat.

C(US)

Legal status
Routes topical (ophthalmic)

Levobetaxolol or Levobetxolol hydrochloride is a drug used to lower the pressure in the eye in treating conditions such as glaucoma. It is typically marketed as a 0.5% ophthalmic solution under the trade name Betaxon. Levobetaxolol is a beta-adrenergic receptor inhibitor (beta blocker.

Additional recommended knowledge

Effect

Levobetaxolol inhibits the beta-1-adrenergic receptor. When applied topically, it reduces intra-ocular pressure (IOP) by 16-23% depending on time of day and the individual. It is indicated for IOP reduction in patients with open-angle glaucoma or ocular hypertension. Levobetaxolol has fewer cardiovascular side effects than other beta blockers.

Contraindications and side effects

Levobetaxolol should not be used by people who have sinus bradycardia, atrioventricular block, cardiogenic shock, or overt cardiac failure.

The drug has been associated with bradycardia and hypertension.

 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Levobetaxolol". A list of authors is available in Wikipedia.
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