Acambis welcomes sanofi pasteur's dengue vaccine progress


Acambis plc welcomes sanofi pasteur's reported progress with a dengue vaccine candidate based on technology licensed from Acambis. Sanofi pasteur, the vaccines division of the sanofi-aventis Group, has announced positive results from Phase 2 trials and plans to start a Phase 3 trial programme in 2008.

The trial results were announced at a Research & Development meeting held in Paris, by sanofi-aventis. During the meeting, dengue fever was highlighted as one of the most common tropical diseases and a growing public health concern. Worldwide, 50-100 million people are affected and cases are appearing in northern Australia and Texas. Sanofi pasteur also highlighted that the potential market for a dengue vaccine could be worth in excess of EUR1bn per annum.

Sanofi pasteur also highlighted that it plans to start a large-scale Phase 3 efficacy study in 2008, making this project the first tetravalent candidate dengue vaccine in the world to reach this stage of clinical development.

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