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Fosazepam is a drug which is a benzodiazepine derivative. It has sedative and anxiolytic effects, and is a derivative of diazepam which has been substituted with a dimethylphosphoryl group to improve solubility in water.
Fosazepam is of relatively low potency compared to other benzodiazepine derivatives, with a 100mg dose of fosazepam equivalent to 10mg of nitrazepam. Fosazepam has similar effects to nitrazepam, but with a shorter duration of action and less tendency to cause rebound insomnia. However fosazepam does produce the long-acting active metabolite nordazepam which might cause extended sedative effects at high doses or with prolonged use, and may produce residual sedation upon awakening.
|This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Fosazepam". A list of authors is available in Wikipedia.|