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Interleukin 19

Crystal structure of human IL-19
Interleukin 19
Symbol IL19
Alt. Symbols , MDA1, ZMDA1, IL-10C
Entrez 29949
HUGO 5990
OMIM 605687
RefSeq NM_153758
UniProt Q9UHD0
Other data
Locus Chr. 1 q32.2

Interleukin-19 is a cytokine that belongs to the IL-10 family of cytokines along with several other interleukins including IL-10, IL-20, IL-22, IL-24, IL-26, and several virus-encoded cytokines. It signals through the same cell surface receptor (IL-20R) that is used by IL-20 and IL-24. The IL-19 gene is expressed in resting monocytes and B cells. It is up-regulated in monocytes following stimulation with granulocyte-macrophage colony-stimulating factor (GM-CSF) or lipopolysaccharide.[1]


  1. ^ Chang, C. et al., Crystal Structure of Interleukin-19 Defines a New Subfamily of Helical Cytokines. Journal of Biological Chemistry, 2003, Volume 278, pages 3308-3313.

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Interleukin_19". A list of authors is available in Wikipedia.
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