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List of bestselling drugs



The following is a list of the top 200 pharmaceutical products ranked by sales.

Rank 2006 Brand Name(s) Generic Name Sales 2006 (USD millions) Change from 2005 Company(ies) Disease/Medical Use First Approval Date
1LipitorAtorvastatin14,3857%Pfizer, Astellas PharmaCholesterolDec-1996
2Advair, SeretideFluticasone + Salmeterol6,12912%GlaxoSmithKlineAsthmaAug-2000
3Plavix, IscoverClopidogrel6,057-5%Bristol-Myers Squibb, Sanofi-AventisThrombotic eventsNov-1997
4NexiumEsomeprazole5,18212%AstraZenecaGastrointestinal disordersMar-2000
5NorvascAmlodipine4,8663%Pfizer HypertensionJul-1992
6RemicadeInfliximab4,42823%Johnson & Johnson, Schering-Plough, TanabeRheumatoid arthritisAug-1998
7EnbrelEtanercept4,37920%Amgen, WyethRheumatoid arthritisNov-1998
8ZyprexaOlanzapine4,3644%Eli Lilly SchizophreniaSep-1996
9DiovanValsartan4,22315%NovartisHypertensionDec-1996
10RisperdalRisperidone4,18318%Johnson & JohnsonSchizophreniaDec-1993
11AranespDarbepoetin alfa4,12126%AmgenAnemiaJun-2001
12Rituxan, MabTheraRituximab3,86116%Roche, Genentech, Biogen Idec, Chugai PharmaceuticalNon-Hodgkin’s lymphomaNov-1997
13EffexorVenlafaxine3,7228%WyethDepressionDec-1993
14Protonix, Pantozol, PantolocPantoprazole3,6214%Wyeth, Altana, SolvayGastrointestinal disordersFeb-2000
15SingulairMontelukast3,57920%Merck & Co.AsthmaFeb-1998
16SeroquelQuetiapine3,56023%AstraZeneca, Astellas PharmaSchizophreniaSep-1997
17Prevacid, TakepronLansoprazole3,4253%TAP Pharmaceuticals, Takeda PharmaceuticalGastrointestinal disordersMay-1995
18Procrit, EprexErythropoietin3,180-4%Johnson & JohnsonAnemiaDec-1990
19Cozaar, HyzaarLosartan3,1634%Merck & Co.HypertensionApr-1995
20FosamaxAlendronate3,134-2%Merck & Co.OsteoporosisSep-1995
21HerceptinTrastuzumab3,13483%Roche, Genentech, Chugai PharmaceuticalBreast cancerSep-1998
22Lovenox, ClexaneEnoxaparin3,05914%Sanofi-AventisDeep-vein thrombosisMar-1993
23Avandia, Avandamet, AvandarylRosiglitazone3,04326%GlaxoSmithKlineType 2 diabetesMay-1999
24ActosPioglitazone2,88025%Takeda Pharmaceutical, Eli Lilly Type 2 diabetesJul-1999
25ZocorSimvastatin2,803-36%Merck & Co.CholesterolDec-1991
26CopaxoneGlatiramer2,75719%Teva Pharmaceutical Industries, Sanofi-AventisMultiple sclerosisDec-1996
27AcipHex, ParietRabeprazole2,729-4%Eisai, Johnson & JohnsonGastrointestinal disordersAug-1999
28NeulastaFilgrastim2,71018%AmgenNeutropeniaJan-2002
29Lexapro, CipralexEscitalopram2,69616%Forest Laboratories, H. LundbeckMajor depressive disorderAug-2002
30Gleevec, GlivecImatinib2,55418%NovartisLeukemiaMay-2001
31Ambien, StilnoxZolpidem2,54533%Sanofi-AventisInsomniaDec-1992
32AriceptDonepezil2,51924%Eisai, PfizerAlzheimer’s diseaseNov-1996
33EpogenErythropoietin2,5112%AmgenAnemiaJun-1989
34Zyrtec, CirrusCetirizine2,3779%Pfizer, UCB, Daiichi SankyoAllergic rhinitisDec-1995
35Avapro, Aprovel, AvalideIrbesartan2,37213%Sanofi-Aventis, Bristol-Myers SquibbHypertensionSep-1997
36AvastinBevacizumab2,36478%Roche, GenentechColorectal cancerFeb-2004
37TaxotereDocetaxel2,2019%Sanofi-AventisCancerOct-1995
38Eloxatin, EloxatineOxaliplatin2,1278%Sanofi-AventisColorectal cancerAug-2002
39ZoloftSertraline2,110-35%Pfizer DepressionDec-1991
40TamifluOseltamivir2,09669%Roche, Chugai PharmaceuticalInfluenzaOct-1999
41LantusInsulin analog2,09337%Sanofi-AventisType 2 diabetes and type 1 diabetesApr-2000
42CrestorRosuvastatin2,04961%AstraZeneca, ShionogiCholesterolNov-2002
43HumiraAdalimumab2,04446%Abbott LaboratoriesRheumatoid arthritisDec-2002
44CelebrexCelecoxib2,03918%Pfizer Osteoarthritis and rheumatoid arthritisDec-1998
45TopamaxTopiramate2,02721%Johnson & JohnsonSeizuresDec-1996
46Prevnarvaccine1,96130%WyethPneumococcal diseaseFeb-2000
47VytorinEzetimibe + Simvastatin1,95590%Merck & Co., Schering-PloughCholesterol Jul-2004
48ZetiaEzetimibe1,92938%Merck & Co., Schering-PloughCholesterol Oct-2002
49WellbutrinBupropion1,92626%GlaxoSmithKline, BiovailDepressionAug-2003
50AbilifyAripiprazole1,9001%Otsuka Pharmaceutical, Bristol-Myers SquibbSchizophreniaNov-2002
51LamictalLamotrigine1,84319%GlaxoSmithKlineSeizuresDec-1994
52Toprol, SelokenMetoprolol1,7953%AstraZenecaHypertensionJan-1992
53NeoRecormon, EpoginErythropoietin1,777-1%Roche, Chugai PharmaceuticalAnemiaJul-1997
54Atacand, BlopressCandesartan1,7688%Takeda Pharmaceutical, AstraZenecaHypertensionOct-1997
55SpirivaTiotropium1,73545%Boehringer IngelheimChronic obstructive pulmonary diseaseApr-2002
56AvonexInterferon beta-1a1,70711%Biogen Idec Multiple sclerosisMay-1996
57ViagraSildenafil1,6571%Pfizer Erectile dysfunctionMar-1998
58MicardisTelmisartan1,64535%Boehringer Ingelheim, Astellas PharmaHypertensionNov-1998
59ActonelRisedronate1,619-4%Procter & Gamble, Sanofi-AventisOsteoporosisMar-1998
60Lupron, LeuplinLeuprolide1,5791%Takeda Pharmaceutical, TAP PharmaceuticalsProstate cancerJan-1989
61TriCor, LipanthylFenofibrate1,56738%Abbott Laboratories, SolvayCholesterolFeb-1998
62ZofranOndansetron1,5673%GlaxoSmithKlineNausea and vomitingDec-1992
63ValtrexValaciclovir1,56324%GlaxoSmithKlineHerpesJun-1995
64Levaquin, FloxinLevofloxacin1,5303%Johnson & Johnson Bacterial infectionsDec-1996
65ArimidexAnastrozole1,50828%AstraZenecaBreast cancerDec-1995
66PrografTacrolimus1,49920%Astellas PharmaTransplant rejectionApr-1993
67CellCeptMycophenolate mofetil1,4708%Roche, Chugai PharmaceuticalTransplant rejectionMay-1995
68Xalatan, XalacomLatanoprost1,4536%Pfizer Intraocular pressureJun-1996
69RebifInterferon beta-1a1,45214%SeronoMultiple sclerosisFeb-1998
70CoregCarvedilol1,44138%GlaxoSmithKlineHypertensionSep-1995
71GemzarGemcitabine1,4085%Eli Lilly CancerMay-1996
72Prilosec, LosecOmeprazole1,371-17%AstraZenecaGastrointestinal disordersSep-1989
73Benicar, OlmetecOlmesartan1,37073%Daiichi Sankyo, Forest LaboratoriesHypertensionApr-2002
74LotrelAmlodipine + Benazepril1,35226%NovartisHypertensionJun-1999
75CymbaltaDuloxetine1,31694%Eli LillyDepressive disorderAug-2004
76Imitrex, ImigranSumatriptan1,3154%GlaxoSmithKlineMigraineDec-1992
77DepakoteValproate1,30819%Abbott LaboratoriesSeizuresMar-1983
78HumalogInsulin analog1,3008%Eli Lilly DiabetesApr-1996
79DuragesicFentanyl1,295-18%Johnson & JohnsonPainAug-1990
80PulmicortBudesonide1,29211%AstraZenecaAsthmaJun-1997
81ZometaZoledronate1,2835%NovartisHypercalcemiaAug-2000
82Betaseron, BetaferonInterferon beta-1b1,24514%Schering AGMultiple sclerosisJul-1993
83Delix, TritaceRamipril1,227-3%Sanofi-AventisHypertensionJul-2000
84Flovent, FlixotideFluticasone1,2195%GlaxoSmithKlineAsthmaMar-1996
85NeupogenFilgrastim1,2130%AmgenNeutropeniaFeb-1991
86CasodexBicalutamide1,2067%AstraZenecaProstate cancerOct-1995
87PravacholPravastatin1,197-47%Bristol-Myers SquibbCholesterolOct-1991
88TruvadaTenofovir + Emtricitabine1,194110%Gilead SciencesHIV infectionAug-2004
89SymbicortBudesonide + Formoterol1,18418%AstraZenecaAsthmaAug-2000
90PegasysPegylated interferon alfa-2a1,1715%Roche, Chugai PharmaceuticalHepatitis CJun-2002
91EvistaRaloxifene1,1594%Eli Lilly, Chugai PharmaceuticalOsteoporosisDec-1997
92FlomaxTamsulosin1,15828%Boehringer IngelheimBenign prostatic hypertrophyOct-1997
93LyricaPregabalin1,156297%PfizerNeuropathic painJul-2004
94Paxil, SeroxatParoxetine1,1473%GlaxoSmithKlineDepressionDec-1992
95KaletraLopinavir1,13513%Abbott LaboratoriesHIV infectionMar-2001
96DetrolTolterodine1,10011%Pfizer Overactive bladderMar-1998
97HarnalTamsulosin1,085-8%Astellas PharmaBenign prostatic hypertrophyJul-1992
98ErbituxCetuximab1,07556%Bristol-Myers Squibb, Merck KGaAColorectal cancerFeb-2004
99SynagisPalivizumab1,065-9%MedImmuneRespiratory syncytial virusJun-1998
100AugmentinCo-amoxiclav1,055-13%GlaxoSmithKlineBacterial infectionsAug-1984
101Premarin, Prempro, PremphaseEstrogen1,05116%WyethMenopausal symptomsNov-1995
102Ortho contraceptivesEstrogen + Progesterone1,016-11%Johnson & JohnsonContraceptionApr-1984
103ZoladexGoserelin1,0080%AstraZenecaProstate cancerDec-1989
104CerezymeImiglucerase1,0078%Genzyme Gaucher diseaseApr-1991
105CravitLevofloxacin1,0022%Daiichi Sankyo, Santen PharmaceuticalBacterial infectionsJun-1909
106YasminDrospirenone99836%Schering AGPrevention of pregnancyAug-2000
107KogenateRecombinant factor VIII98919%Bayer HemophiliaFeb-1993
108BotoxBotulin toxin98218%Allergan Cervical dystoniaDec-1989
109LamisilTerbinafine978-14%NovartisFungal infectionsDec-1992
110CombivirLamivudine + Zidovudine977-8%GlaxoSmithKlineHIV infectionSep-1997
111Zosyn, TazocinPiperacillin9729%WyethBacterial infectionsOct-1993
112CialisTadalafil97130%Lilly, Lilly IcosErectile dysfunctionNov-2002
113KeppraLevetiracetam95636%UCB SeizuresNov-1999
114NovoSevenFactor VII94811%Novo Nordisk Bleeding due to hemophiliaFeb-1996
115Infanrix, Pediarixvaccine94521%GlaxoSmithKlineDiphtheria, tetanus, and pertussisJan-1996
116NasonexMometasone94428%Schering-Plough Allergic rhinitisOct-1997
117ReyatazAtazanavir93134%Bristol-Myers SquibbHIV infectionJan-2003
118ConcertaMethylphenidate93020%Johnson & JohnsonAttention-deficit hyperactivity disorderAug-2000
119HumulinRecombinant human insulin925-8%Eli Lilly DiabetesOct-1982
120Neoral, SandimmunCiclosporin918-4%NovartisTransplant rejectionJul-1995
121SandostatinSomatostatin9152%NovartisAcromegalyOct-1988
122CamptosarIrinotecan903-1%Pfizer Colorectal cancerJun-1996
123Engerix-B, Havrix, Twinrixvaccine88610%GlaxoSmithKlineHepatitisAug-1989
124Allegra, TelfastFexofenadine864-49%Sanofi-AventisAllergic rhinitisJul-1996
125AdderallAmphetamine86418%Shire PharmaceuticalsAttention-deficit hyperactivity disorderOct-2001
126CombiventIpratropium + Salbutamol84320%Boehringer IngelheimChronic obstructive pulmonary diseaseOct-1996
127Peg-IntronPegylated interferon alfa-2b83711%Schering-Plough Hepatitis CMay-2000
128AdalatNifedipine8250%Bayer HypertensionNov-1985
129Avelox, AvaloxMoxifloxacin82217%Bayer, Schering-Plough, ShionogiBacterial infectionsDec-1999
130MobicMeloxicam818-66%Boehringer Ingelheim, Daiichi SankyoOsteoarthritis and rheumatoid arthritisFeb-1996
131BiaxinClarithromycin816-23%Abbott LaboratoriesBacterial infectionsOct-1991
132MevalotinPravastatin799-35%Daiichi Sankyo CholesterolJun-1909
133Ultane, SevoraneSevoflurane799-9%Abbott LaboratoriesAnesthesiaJun-1995
134GenotropinSomatropin 795-2%Pfizer Growth failureAug-1995
135SustivaEfavirenz79116%Bristol-Myers SquibbHIV infectionSep-1998
136ZyvoxLinezolid78227%PfizerBacterial infectionsApr-2000
137XelodaCapecitabine77522%Roche, Chugai PharmaceuticalCancerJun-1909
138Geodon, ZeldoxZiprasidone75829%Pfizer SchizophreniaFeb-2001
139Cipro, CiprobayCiprofloxacin755-6%Bayer, Schering-PloughBacterial infectionsOct-1987
140ProvigilModafinil73543%CephalonSleepinessDec-1998
141LescolFluvastatin725-5%NovartisCholesterolDec-1993
142Clarinex, AeriusDesloratadine72212%Schering-Plough Allergic rhinitisDec-2001
143FemaraLetrozole72235%Novartis, Chugai PharmaceuticalBreast cancerJul-1997
144TrileptalOxcarbazepine72117%NovartisSeizuresNov-1999
145TracleerBosentan71742%ActelionPulmonary arterial hypertensionNov-2001
146PrimaxinImipenem + Cilastatin705-5%Merck & Co.Bacterial infectionsNov-1985
147TemodarTemozolomide70320%Schering-PloughAnaplastic astrocytomaAug-1999
148Trusopt, CosoptDorzolamide69713%Merck & Co.Intraocular pressureDec-1994
149VoltarenDiclofenac6900%NovartisOsteoarthritis and rheumatoid arthritisJul-1998
150VireadTenofovir689-12%Gilead SciencesHIV infectionOct-2001
151SifrolPramipexole67323%Boehringer IngelheimParkinson’s diseaseOct-1997
152NamendaMemantine66030%Forest LaboratoriesAlzheimer diseaseOct-2003
153AltaceRamipril65318%King PharmaceuticalsCardiovascular eventsJan-1991
154ByettaExenatide649464%Amylin Pharmaceuticals, Eli Lilly Type 2 diabetesApr-2005
155TarcevaErlotinib649110%Roche, GenentechNon-small cell lung cancerNov-2004
156Zithromax, ZmaxAzithromycin638-68%Pfizer Bacterial infectionsNov-1991
157OmnicefCefdinir63729%Abbott LaboratoriesBacterial infectionsDec-1997
158ProscarFinasteride619-16%Merck & Co.Benign prostatic hypertrophyJun-1992
159AlimtaPemetrexed61232%Eli LillyNon-small cell lung cancerFeb-2004
160MerremMeropenem60420%AstraZenecaBacterial infectionsJun-1996
161ForteoTeriparatide59453%Eli LillyOsteoporosisNov-2002
162StratteraAtomoxetine5795%Eli Lilly Attention-deficit hyperactivity disorderNov-2002
163ActiqFentanyl57840%CephalonCancer painNov-1998
164Flonase, FlixonaseFluticasone575-52%GlaxoSmithKlineAllergic rhinitisOct-1994
165AmarylGlimepiride567-33%Sanofi-AventisType 2 diabetesNov-1995
166LidodermLidocaine56735%Endo PharmaceuticalsPainMar-1999
167LunestaEszopiclone56772%SepracorInsomniaDec-2004
168Boniva, BonvivaIbandronate565454%Roche, GlaxoSmithKlineOsteoporosisMar-2005
169TaxolPaclitaxel563-25%Bristol-Myers SquibbCancerDec-1992
170Zelnorm, ZelmacTegaserod56134%NovartisIrritable bowel syndromeMar-2002
171RenagelSevelamer55923%Genzyme, Roche, Chugai PharmaceuticalHyperphosphatemiaOct-1998
172NorditropinHuman growth hormone55719%Novo Nordisk Growth hormone deficiencyJun-1909
173XopenexLevalbuterol55529%SepracorBronchospasmMar-1999
174XenicalOrlistat5539%RocheObesityJul-1998
175Vasotec, VasereticEnalapril547-12%Merck & Co.HypertensionDec-1985
176SereventSalmeterol538-10%GlaxoSmithKlineAsthmaFeb-1994
177CarduraDoxazosin538-8%Pfizer HypertensionNov-1990
178SynthroidLevothyroxine534-4%Abbott LaboratoriesHypothyroidismMay-1909
179Gonal-fFollitropin alfa533-3%SeronoInfertilityOct-1995
180GasterFamotidine532-10%Astellas PharmaGastrointestinal disordersJun-1909
181CancidasCaspofungin530-7%Merck & Co.Fungal infectionsJan-2001
182ExelonRivastigmine52512%NovartisAlzheimer’s diseaseMay-1998
183VfendVoriconazole51530%PfizerFungal infectionsMar-2002
184AmlodinAmlodipine5064%Dainippon SumitomoHypertension, angina pectorisn/a
185NiaspanNiacin49813%Kos PharmaceuticalsCholesterolJul-1997
186NeurontinGabapentin496-22%Pfizer SeizuresDec-1993
187TrizivirAbacavir + Lamivudine + Zidovudine496-10%GlaxoSmithKlineHIV infectionNov-2000
188RequipRopinirole49674%GlaxoSmithKlineParkinson diseaseSep-1997
189Follistim, PuregonFollitropin beta4828%Akzo NobelInfertilitySep-1997
190BasenVoglibose476-13%Takeda PharmaceuticalHyperglycemiaJun-1909
191LevitraVardenafil47419%Bayer, GlaxoSmithKlineErectile dysfunctionMar-2003
192GlucophageMetformin459-16%Merck KGaA, Bristol-Myers SquibbType 2 diabetesDec-1994
193ConcorBisoprolol4554%Merck KGaAHypertensionJul-1992
194Epzicom, KixevaAbacavir + Lamivudine446107%GlaxoSmithKlineHIV infectionAug-2004
195XatralAlfuzosin4438%Sanofi-AventisBenign prostatic hypertrophyJan-2000
196DiflucanFluconazole435-13%Pfizer Fungal infectionsJan-1990
197ThalomidThalidomide43312%CelgeneErythema nodosum leprosum Jul-1998
198ZantacRanitidine429-18%GlaxoSmithKline Gastrointestinal disordersJun-1983
199XolairOmalizumab42932%Roche, GenentechAsthmaJun-2003
200ClaritinLoratadine418-5%Schering-Plough, ShionogiAllergic rhinitisApr-1993

Additional recommended knowledge

Source: MedAdNews 200 - World's Best-Selling Medicines, MedAdNews, July 2007

 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "List_of_bestselling_drugs". A list of authors is available in Wikipedia.
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