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MEF2C (Myocyte enhancer factor 2C) is a transcription factor in the Mef2 family.[1] The Mef2c gene is necessary for proper embryonic development: mice without a functional copy of the Mef2c gene die before birth and have abnormalities in the heart and vascular system.[2]


  1. ^ Molkentin JD, Black BL, Martin JF, Olson EN (1996). "Mutational analysis of the DNA binding, dimerization, and transcriptional activation domains of MEF2C.". Mol Cell Biol. 16 (6): 2627-36. PMID 8649370.
  2. ^ Bi W, Drake CJ, Schwarz JJ (1999). "The transcription factor MEF2C-null mouse exhibits complex vascular malformations and reduced cardiac expression of angiopoietin 1 and VEGF". Developmental Biology 211 (2): 255-67. PMID 10395786.

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Mef2c". A list of authors is available in Wikipedia.
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