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Core binding factor

Core binding factors (CBFs) comprise a group of heterodimeric transcription factors.

They are composed of:

  • a non-DNA-binding CBFβ chain (CBFB)
  • a DNA-binding CBFα chain (RUNX1, RUNX2, RUNX3)


  • de Bruijn M, Speck N (2004). "Core-binding factors in hematopoiesis and immune function". Oncogene 23 (24): 4238-48. PMID 15156179.
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Core_binding_factor". A list of authors is available in Wikipedia.
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