CD29

Integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
Identifiers
Symbol(s)	ITGB1; CD29; FNRB; GPIIA; MDF2; MSK12; VLAB
External IDs	OMIM: 135630 MGI: 96610 Homologene: 22999
Gene Ontology Molecular Function: • receptor activity • protein binding • identical protein binding • protein heterodimerization activity Cellular Component: • ruffle • endoplasmic reticulum • integrin complex • membrane • integral to membrane Biological Process: • cellular defense response • cell adhesion • homophilic cell adhesion • cell-matrix adhesion • integrin-mediated signaling pathway • multicellular organismal development • cell migration
RNA expression pattern
Additional recommended knowledge Recognize and detect the effects of electrostatic charges on your balance Don't let static charges disrupt your weighing accuracy Correct Test Weight Handling Guide: 12 Practical Tips More reference expression data
Orthologs
	Human	Mouse
Entrez	3688	16412
Ensembl	ENSG00000150093	ENSMUSG00000025809
Uniprot	P05556	Q3TIW5
Refseq	NM_002211 (mRNA) NP_002202 (protein)	NM_010578 (mRNA) NP_034708 (protein)
Location	Chr 10: 33.23 - 33.29 Mb	Chr 8: 131.59 - 131.62 Mb
Pubmed search	[1]	[2]

Integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12), also known as ITGB1 or CD29, is a human gene. CD29 is an integrin unit associated with very late antigen receptors.

Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metatastatic diffusion of tumor cells. The protein encoded by this gene is a beta subunit. Six alternatively spliced variants have been found for this gene which encode five proteins with alternate carboxy termini.^[1]

References

Further reading