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Ethamivan



Ethamivan
Systematic (IUPAC) name
N,N-diethyl-4-hydroxy-3-methoxybenzamide
Identifiers
CAS number 304-84-7
ATC code  ?
PubChem 9363
Chemical data
Formula C12H17NO3 
Mol. mass 223.268
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

?

Legal status
Routes  ?

Ethamivan (Analepticon) is a respiratory stimulant drug[1] related to nikethamide. It was mainly used in the treatment of barbiturate overdose[2] and chronic obstructive pulmonary disease,[3] but has now largely fallen into disuse. Some research suggests that it may have abuse potential.[4]




References

  1. ^ Hirsh K, Wang SC. Respiratory stimulant effects of ethamivan and picrotoxin. Journal of Pharmacology and Experimental Therapeutics. 1975 May;193(2):657-63.
  2. ^ Wheeldon PJ, Perry AW. The use of ethamivan in the treatment of barbiturate poisoning. Canadian Medical Association Journal. 1963 Jul 6;89:20-2.
  3. ^ Sproule BJ, Jans RL, Breitkreutz H, Mahon W. Effects of ethamivan in patients with chronic respiratory disease. Canadian Medical Association Journal. 1964 Dec 5;91:1203-8.
  4. ^ Ma C, Duan H, Zhang H, Xu Y, Zhou T. Studies on analytical method for 10 drugs of abuse in urine using HPLC. (Chinese) Yao Xue Xue Bao. 1998 Oct;33(10):764-7.
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Stimulants
EugeroicsAdrafinil • Armodafinil • Carphedon • Modafinil
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Piperazines

BZP • MeOPP • MBZP • mCPP • 2C-B-BZP

XanthinesCaffeine • Aminophylline • Paraxanthine • Theobromine • Theophylline
Tropanes

Brasofensine • CFT • Cocaethylene • Cocaine • Lometopane • RTI-121 • Tesofensine • Troparil

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ConvulsantsBicuculline • Gabazine • Pentetrazol • Picrotoxin • Strychnine • Thujone
Phenylaminooxazoles
Others
See also Sympathomimetic amines
 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Ethamivan". A list of authors is available in Wikipedia.
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