MorphoSys Unveils New Antibody Library


MorphoSys AG (Neuer Markt: MOR) today announced the development and release of a new proprietary antibody library, HuCAL® GOLD. The library is to be presented at the 12th IBC Antibody Engineering conference in San Diego, California. Initial results show that the new library and related screening system lead to faster and more efficient antibody generation, as well as enabling the achievement of higher average affinity antibodies and more diverse fully human antibodies. Furthermore, the new library increases the Company's independence from several on-going patent disputes.

HuCAL® GOLD contains several significant innovations over previous versions of the HuCAL® library and is combined with the Company's proprietary CysDisplayTM screening technology. Importantly, the new library carries diverse repertoires in all six CDR regions of the underlying antibody genes, meaning that HuCAL® GOLD provides more diversity than previous versions. Moreover in combination with the CysDisplayTM

"HuCAL® GOLD is the culmination of several years of technological development of our proprietary HuCAL® platform" commented Dr. Thomas von Rueden, Chief Scientific Officer of MorphoSys AG. "We already have good evidence that its superior properties enable us to make better antibodies. Of equal importance is the fact that most of the technology underlying HuCAL® GOLD is proprietary to MorphoSys and independent of other technologies - thus the new library clarifies even further our IP position."

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