My watch list
my.chemeurope.com  
Login  

Diethylthiambutene



Diethylthiambutene
Systematic (IUPAC) name
N,N-diethyl-4,4-dithiophen-2-yl-but-3-en-2-amine
Identifiers
CAS number 86-14-6
ATC code  ?
PubChem 149833
Chemical data
Formula C16H21NS2 
Mol. mass 291.477 g/mol
SMILES search in eMolecules, PubChem
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

?

Legal status

Schedule I(US)

Routes  ?

Diethylthiambutene (Thiambutene, Themalon, Diethibutin, N,N-Diethyl-1-methyl-3,3-di-2-thienylallylamine) is an opioid analgesic drug developed in the 1950s [1] which was mainly used as an anesthetic in veterinary medicine.[2][3] It is now under international control under Schedule I of the UN Single Convention On Narcotic Drugs 1961, presumably due to high abuse potential, although little more information is available.

Additional recommended knowledge

References

  1. ^ BECKETT AH, CASY AF, HARPER NJ, PHILLIPS PM. Analgesics and their antagonists: some steric and chemical considerations. II. The influence of the basic group on physico-chemical properties and the activity of methadone and thiambutene-type compounds. Journal of Pharmacy and Pharmacology. 1956 Nov;8(11):860-73.
  2. ^ Hayes MJ. The use of thiambutene hydrochloride. The Veterinary Record. 1968 Nov 16;83(20):528.
  3. ^ Harbison WD, Slocombe RF, Watts SJ, Stewart GA. Thiambutene and acepromazine as analgesic and preanaesthetic agents in horses and sheep. Australian Veterinary Journal. 1974 Dec;50(12):543-6.



 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Diethylthiambutene". A list of authors is available in Wikipedia.
Your browser is not current. Microsoft Internet Explorer 6.0 does not support some functions on Chemie.DE