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Hydroxypethidine



Hydroxypethidine
Systematic (IUPAC) name
Ethyl 4-(3-hydroxyphenyl)-1-methyl-piperidine-4-carboxylate
Identifiers
CAS number 468-56-4
ATC code  ?
PubChem 61120
Chemical data
Formula C15H21NO3 
Mol. mass 263.332 g/mol
Synonyms Hydroxypethidine, Bemidone
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

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Legal status
Routes  ?

Hydroxypethidine (Bemidone) is an opioid analgesic that is an analogue of pethidine (meperidine). Hydroxypethidine is significantly less potent than meperidine as an analgesic, (0.3x meperidine in potency) although it also has NMDA antagonist properties like its close relative ketobemidone. [1]

Additional recommended knowledge

Hydroxypethidine has similar effects to other opioids, and produces analgesia, sedation and euphoria. Side effects can include itching, nausea and potentially serious respiratory depression which can be life-threatening.

References

  1. ^ Isbell Harris. The addiction liability of some analogues of meperidine. Journal of Pharmacology And Experimental Therapeutics, 1949; 97(2): 182-190


 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Hydroxypethidine". A list of authors is available in Wikipedia.
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