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Pethidinic Acid (Meperidinic Acid, Pethidine Intermediate C) is a 4-phenylpiperidine derivative that is both a metabolite of and a precursor to pethidine (meperidine).
Additional recommended knowledge
Pethidinic acid is a controlled drug because of its potential uses in manufacturing both pethidine itself and some of its substituted derivatives, but it has little opioid activity in its own right. Metabolism of pethidine to pethidinic acid is carried out mainly by the carboxylesterase enzyme hCE-1 in the liver, and since the activity of this enzyme can vary between individuals, the rate and extent of pethidinic acid production can vary.
|This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Pethidinic_Acid". A list of authors is available in Wikipedia.|