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Additional recommended knowledge
Difenoxin is an active metabolite of the anti-diarrhea drug diphenoxylate. It is not used by itself and is a Schedule I drug in the USA, however in some countries a combination product containing difenoxin and atropine is used to treat diarrhea, in a similar way to how diphenoxylate itself is used.
Difenoxin also has some sedative and analgesic effects as with other opioids, but diphenoxylate itself is a relatively weak analgesic, and difenoxin has similarly limited analgesic effects, although it is a potent anti-diarrhoreal drug. Research suggests that additional non-opioid mechanisms may also be involved in the action of difenoxin, explaining its strong anti-diarrhoreal effects despite only limited opioid action.
|This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Difenoxin". A list of authors is available in Wikipedia.|