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Nicodicodeine is an opiate derivative developed as a cough suppressant and analgesic. It is not commonly used, but has activity similar to other opiates. Nicodicodeine is metabolised in the liver by demethylation to produce 6-nicotinoyldihydromorphine, and subsequently further metabolised to dihydromorphine. Since the final active metabolite is the slightly stronger opiate dihydromorphine rather than morphine, nicodicodeine can be expected to be marginally more potent and longer acting than nicocodeine. Side effects are similar to those of other opiates and include itching, nausea and respiratory depression.
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|This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Nicodicodeine". A list of authors is available in Wikipedia.|