My watch list
my.chemeurope.com  
Login  

Nicodicodeine



Nicodicodeine
Systematic (IUPAC) name
?
Identifiers
CAS number 808-24-2
ATC code  ?
PubChem 5464304
Chemical data
Formula C24H26N2O4 
Mol. mass 406.474 g/mol
Synonyms Nicodicodine, 6-Nicotinoyldihydrocodeine
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

?

Legal status

Schedule I(US)

Routes Oral, intravenous

Nicodicodeine is an opiate derivative developed as a cough suppressant and analgesic. It is not commonly used, but has activity similar to other opiates. Nicodicodeine is metabolised in the liver by demethylation to produce 6-nicotinoyldihydromorphine, and subsequently further metabolised to dihydromorphine. Since the final active metabolite is the slightly stronger opiate dihydromorphine rather than morphine, nicodicodeine can be expected to be marginally more potent and longer acting than nicocodeine. Side effects are similar to those of other opiates and include itching, nausea and respiratory depression.

Additional recommended knowledge


 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Nicodicodeine". A list of authors is available in Wikipedia.
Your browser is not current. Microsoft Internet Explorer 6.0 does not support some functions on Chemie.DE